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Hedgehog 信号通路基因表达 PCR 芯片可检测 hedgehog 信号通路相关的 84 个基因。芯片中包含 hedgehog 家族成、hedgehog 受体和其他相关蛋白，以及与细胞分化和多细胞生物发育相关的关键基因。利用该芯片研究者即能够利用该芯片简单可靠地同时检测 hedgehog 信号相关的基因表达。
Hedgehog Signaling Pathway: Hedgehog Ligands & Regulators: BOC, CDON, DHH, GAS1, HHIP, IHH, SHH.
Hedgehog Receptors & Cofactors: LRP2, PTCH1, PTCH2, PTCHD1, PTCHD2, PTCHD3, RAB23, SMO.
Transcription Factors & Regulators: BTRC, CSNK1A1, CSNK1E, FBXW11, GLI1, GLI2, GLI3, GSK3B, PRKACA, PRKACB, STK36, SUFU, ZIC1, ZIC2 (HPE5).
Other Genes Important for Hedgehog Signaling: DISP1, DISP2, FGF9, FKBP8, HHAT, IFT52, KCTD11, OTX2, NPC1.
Target Genes: BCL2, BMP2, BMP4, BMP5, BMP6, BMP7, BMP8B, MTSS1, PTCH1, PTCH2, WNT1, WNT10A, WNT10B, WNT11, WNT16, WNT2, WNT2B, WNT3, WNT3A, WNT4, WNT5A, WNT5B, WNT6, WNT7A, WNT7B, WNT8A, WNT8B, WNT9A, WNT9B, VEGFA.
Pathways that Crosstalk with Hedgehog Signaling: TGFß/BMP
Signaling: BMP2, BMP4, BMP5, BMP6, BMP7, BMP8B, GREM1, SFRP1.
WNT Signaling: BTRC, CTNNB1, FBXW11, FGF9, GSK3B, LATS1, LATS2, WIF1, WNT1, WNT10A, WNT10B, WNT11, WNT16, WNT2, WNT2B, WNT3, WNT3A, WNT4, WNT5A, WNT5B, WNT6, WNT7A, WNT7B, WNT8A, WNT8B, WNT9A, WNT9B.
Hippo Signaling: FAT4, FRMD6, LATS1, LATS2, MOBKL1A, NF2, STK3.
Other Genes: FGFR3, RUNX2, ERBB4, FOXE1, MAPK1 (ERK2), NUMB, TP53.