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表观遗传染色体重构因子基因表达 PCR 芯片可用于研究参与染色体修改和染色体重构的识别进而调控染色体转录活性的 84 个关键基因的表达。利用该芯片研究者即能够利用该芯片简单可靠地同时检测参与染色体重构有关的基因表达。
SWI/SNF Complex Components: ARID1A, INO80 (INOC1), PBRM1, SMARCA2, SMARCA4.
Polycomb Group Genes: ASXL1, BMI1 (PCGF4), CTBP1, CTBP2, EED, EZH2, PCGF1, PCGF2, PCGF3, PCGF5, PCGF6, PHC1, PHC2, RING1, RNF2, SUZ12, TRIM27.
Chromobox / Heterochromatin Protein 1 (HP1) Homologs: CBX1, CBX3, CBX4, CBX5, CBX6, CBX7, CBX8.
Bromodomain Proteins: BAZ1A, BAZ1B, BAZ2A, BAZ2B, BPTF, BRD1, BRD2, BRD3, BRD4, BRD7, BRD8, BRDT, BRPF1, BRPF3, BRWD1, WDR11, BRWD3, ZMYND8.
Chromodomain / Helicase / DNA-Binding Domain (CHD) Proteins: CDYL, CDYL2, CHD1, CHD2, CHD3, CHD4, CHD5, CHD6, CHD7, CHD8, CHD9.
Nucleosome-Remodeling and Histone Deacetylase (NuRD) Complex Components: CHD3, MBD3, MTA1, MTA2, NAB2, SPEN.
Plant Homeodomain (PHD) Proteins: NSD1, PHF1, PHF2, PHF3, PHF5A, PHF6, PHF7, PHF13, PHF21A, PHF21B.
Inhibitor of Growth (ING) Family Members: ING1, ING2, ING3, ING4, ING5, RING1.
Methyl-CpG DNA Binding Domain (MDB) Proteins: MBD1, MBD2, MBD3, MBD4, MECP2, HINFP.
CCCTC-Binding Factor (Zinc Finger Protein): CTCF.