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cAMP/Ca2+ 通路发现者基因表达 PCR 芯片可用于研究参与 cAMP/Ca2+应答的 84 的关键基因的表达。该芯片所包含的基因，其启动子区域具有 SRE 或 SRE-like 增强子序列、CRE 增强子序列或其他 Ca2+应答元素。利用该芯片研究者即能够利用该芯片简单可靠地同时检测 cAMP/Ca2+信号通路相关基因的表达。
Genes whose promoters contain SRE or SRE-like enhancer sequences: CNN1 (calponin), CYR61, EGR1, EGR2, FOS, FOSB, HSPA4 (hsp70), JUNB, NR4A2 (Nur77), S100A6 (Calcyclin), SCG2 (secretogranin II), SRF, THBS1 (TSP-1), VCL.
Genes whose promoters contain the CRE enhancer sequence: Neuropeptides / Neurotransmitters: ADRB1 (b1 adrenergic receptor), CGA (Chorionic gonadotropin A), CHGA (Chromogranin), GCG (Glucagon), GIPR, INHBA (Inhibin A), KCNA5 (KV1.5), NOS2 (Inducible nitric oxide synthase), PENK (Enkephalin), PRL, S100A12 (CGRP), S100G, SCG2, SLC18A1 (Vesicular monoamine transporter), SST (Somatostatin), SSTR2 (Somatostatin receptor 2), TACR1 (Substance P receptor), TH (Tyrosine hydroxylase), VIP.
Cell Cycle / Cell Survival / DNA RePAir: BCL2, BRCA1, CCNA1 (CyclinA), CCND1 (CyclinD1), CDK5, CDKN2B (p15IND4b), GEM, NF1, PCNA, PMAIP1 (NoxA), PPP1R15A (GADD34), RB1.
Growth Factor: AREG (Amphiregulin), BDNF, CTF1 (Cardiotrophin), FGF6, TGFB3, TNF.
Signaling: DUSP1 (Ptpn16), HSPA5 (Grp78), PLN (Phospholamban), PPP2CA (Protein phosphatase 2A alpha), PRKAR1A (Proteinkinase A regulatory subunit), SGK1.
Transcription: ATF3, CREB1, CREM, EGR1, EGR2, FOS, JUND, MAF, NR4A2 (Nur77), PER1, POU1F1 (Pit-1), POU2AF1 (OCA- B), STAT3.
Metabolism: AHR, AMD1, ENO2, HK2, LDHA, PCK2, SOD2.
Immune Regulation: IL2, IL6, MIF, PTGS2 (Cox-2).
Genes whose promoters contain other Ca2+ responsive elements: CALB1 (calbindin 1), CALB2 (calbindin 2), CALM1 (Calmodulin 1), CALR (Calreticulin), DDIT3 (GADD153), NCAM1, NPY, PLAT (tPA).